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Importantly, these receptors have been uncovered to have been activated by a wide range of endogenous opioids at a concentration much like that observed for activation and signaling of classical opiate receptors. In turn, these receptors were discovered to possess scavenging activity, binding to and lowering endogenous levels of opiates readily ava
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Researchers have a short while ago discovered and succeeded in synthesizing conolidine, a purely natural compound that demonstrates guarantee as a powerful analgesic agent with a far more favorable basic safety profile. Even though the actual system of action remains elusive, it really is now postulated that conolidine could have numerous biologic